# Combining computer‐based rehabilitative approach with tDCS for recovering of aphasia: Implications from a single case study

**Authors:** Marianna Contrada, Federica Scarfone, Antonella Iozzi, Simone Carozzo, Martina Vatrano, Maria Grazia Nicoletta, Giuseppe Nudo, Maria Quintieri, Paolo Tonin, Antonio Cerasa

PMC · DOI: 10.1002/ccr3.8928 · Clinical Case Reports · 2024-05-22

## TL;DR

A patient with aphasia showed improved language and swallowing after combining tDCS with a VR rehabilitation system.

## Contribution

Preliminary evidence that combining tDCS and computer-based rehab improves aphasia recovery.

## Key findings

- Improvements in oral and written language comprehension after treatment.
- Significant enhancement of θ, α, and β EEG waves post-treatment.
- Reduction in caregiver burden and improved swallowing abilities observed.

## Abstract

We present a case of a single left hemisphere temporal–parietal stroke with subacute global aphasia and severe verbal apraxia and moderate dysphagia. The patient underwent a combined transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) and language stimulation with Virtual Reality Rehabilitation System (VRRS). Patient was treated in a 1‐h session, for 5 days a week, for 4 consecutive weeks. After treatment, evident improvements in the comprehension of oral and written language, swallowing abilities, and caregiver burden were detected. Power spectrum analysis of EEG data revealed significant enhancements of θ, α, and β waves from baseline to follow‐up. These preliminary results seem to confirm the reliability of the tDCS translational application in conjunction with computer‐based cognitive treatment for language disorders in a patient with stroke‐induced aphasia.

## Linked entities

- **Diseases:** aphasia (MONDO:0000598), stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** dysphagia (MESH:D003680), aphasia (MESH:D001037), verbal apraxia (MESH:D001072), language disorders (MESH:D007806), stroke (MESH:D020521)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11111603/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11111603/full.md

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Source: https://tomesphere.com/paper/PMC11111603