# In the Shadows of Rarity: A Case Report of Syndromic Cleft Lip and Palate!

**Authors:** Pallavi Daigavane, Mrudula Shinde, Priyanka Niranjane, Bhagyashri Chimote

PMC · DOI: 10.7759/cureus.58752 · Cureus · 2024-04-22

## TL;DR

This paper presents a rare case of cleft lip and palate associated with other physical abnormalities, emphasizing the need for thorough diagnosis.

## Contribution

The case highlights the importance of identifying syndromic connections in cleft lip and palate patients.

## Key findings

- The patient exhibited polydactyly, camptodactyly, and pelvic abnormalities alongside cleft lip and palate.
- Comprehensive screening is crucial for diagnosing syndromic cleft conditions.

## Abstract

Deviations from normal craniofacial development can result in a range of abnormalities, including cleft lip and/or palate, either as standalone conditions or as components of syndromes with varying clinical characteristics. The ability to distinguish between isolated incidents and syndromes with clefts as one component is integral to achieving accurate diagnosis and therapy.

The following case presentation highlights the importance of comprehensive screening and differential diagnosis in identifying syndromic connections in patients with cleft lip and palate. In this specific case, the patient presented with polydactyly, camptodactyly, and pelvic area abnormalities, indicating a possible syndromic connection with cleft lip and/or palate.

## Linked entities

- **Diseases:** cleft lip and palate (MONDO:0016044)

## Full-text entities

- **Diseases:** polydactyly (MESH:D017689), camptodactyly (MESH:C567780), pelvic area abnormalities (MESH:D034161), Cleft Lip and Palate (MESH:D002971)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11110944/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11110944/full.md

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Source: https://tomesphere.com/paper/PMC11110944