# Duodenal Carcinosarcoma: An Apple-Core Lesion Causing Gastric Outlet Obstruction

**Authors:** Eli A Zaher, Mohamed A Ebrahim, Yasmin Gerais, Parth Patel, Omar Al Salman

PMC · DOI: 10.7759/cureus.58725 · Cureus · 2024-04-22

## TL;DR

A rare case of duodenal carcinosarcoma in a 58-year-old man highlights the challenges in diagnosing and treating this aggressive tumor.

## Contribution

This report adds to the limited literature on duodenal carcinosarcomas, emphasizing their clinical presentation and management difficulties.

## Key findings

- Duodenal carcinosarcoma is a rare tumor with only 12 documented cases in the literature.
- Surgical resection is the primary treatment, but prognosis remains poor despite intervention.
- The tumor's mixed carcinomatous and sarcomatous elements complicate diagnosis and treatment strategies.

## Abstract

We present a case of a 58-year-old male with a rare duodenal carcinosarcoma causing gastric outlet obstruction. Despite its aggressive nature and poor prognosis, with only 12 documented cases in the literature, this report sheds light on the clinical presentation and challenges in diagnosis and treatment. Carcinosarcoma, characterized by both carcinomatous and sarcomatous elements, poses difficulties in management due to its diverse tissue characteristics. Surgical resection remains the primary treatment, although the prognosis remains grim, emphasizing the need for further research into advanced therapeutic strategies to improve patient outcomes. This case underscores the rarity and clinical complexities associated with duodenal carcinosarcomas.

## Linked entities

- **Diseases:** gastric outlet obstruction (MONDO:0001561)

## Full-text entities

- **Diseases:** carcinomatous (MESH:D055756), Carcinosarcoma (MESH:D002296), Gastric Outlet Obstruction (MESH:D017219)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11110488/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11110488/full.md

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Source: https://tomesphere.com/paper/PMC11110488