# Undifferentiated Pleomorphic Sarcoma of the Distal Thigh: A Case Report

## TL;DR

A 40-year-old man was diagnosed with undifferentiated pleomorphic sarcoma, a rare cancer typically found in older adults, highlighting the uniqueness of this case.

## Contribution

This case report presents an atypical UPS diagnosis in a younger individual, offering insights into its clinical presentation and management.

## Key findings

- UPS was diagnosed in a 40-year-old male, which is unusual as it typically affects older adults.
- The case emphasizes the importance of biopsy and imaging in diagnosing UPS.
- Standard treatments like surgery and chemotherapy were considered for this patient.

## Abstract

The undifferentiated pleomorphic sarcoma (UPS) is a rare malignant tumor of mesenchymal origin. Poorly differentiated tumor cells, which might take the form of giant cells, histiocytes, or spindle-shaped cells, make up the UPS variant of sarcomas. If soft tissue tumors enlarge and turn malignant, they may become an issue. Sarcoma is diagnosed by several tests, such as a physical examination, MRI, CT scan, or ultrasound. A biopsy yields information regarding the grade and subtype of the sarcoma and is required for a clear diagnosis. Chemotherapy, radiation therapy, and broad-margin excision are the standard treatments for cancers of the bone.

UPS often appears in people between 50 and 70 years old. Yet, here we report a 40-year-old male diagnosed with UPS. Our goal is to discuss how unique our case is in comparison to others, as well as the available diagnostic and therapeutic alternatives in such cases.