# Hepatitis C Virus Clearance and Diffusing Capacity for Carbon Monoxide in Women With and Without Human Immunodeficiency Virus

**Authors:** Andrew C Curnow, Laurence Huang, Margaret A Fischl, Michelle Floris-Moore, Alison Morris, Mehdi Nouraie, Divya B Reddy, Eric C Seaberg, Anandi N Sheth, Phyllis C Tien, Richard J Wang

PMC · DOI: 10.1093/ofid/ofae251 · Open Forum Infectious Diseases · 2024-05-02

## TL;DR

This study found no link between clearing hepatitis C virus and improved lung function in women with and without HIV.

## Contribution

The study is the first to investigate the effect of HCV clearance on lung diffusing capacity in women with and without HIV.

## Key findings

- HCV clearance was not associated with improved diffusing capacity for carbon monoxide.
- No significant differences in lung function were observed after HCV clearance in the study population.

## Abstract

Hepatitis C virus (HCV) infection is associated with extrahepatic effects, including reduced diffusing capacity of the lungs. It is unknown whether clearance of HCV infection is associated with improved diffusing capacity. In this sample of women with and without human immunodeficiency virus, there was no association between HCV clearance and diffusing capacity.

## Linked entities

- **Chemicals:** carbon monoxide (PubChem CID 281)

## Full-text entities

- **Diseases:** HCV infection (MESH:D006526)
- **Chemicals:** Carbon Monoxide (MESH:D002248)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human immunodeficiency virus (species) [taxon 12721]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11103618/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC11103618/full.md

---
Source: https://tomesphere.com/paper/PMC11103618