# How to switch on a master switch **Authors:** Navneet Kaur, Nigel G Halford PMC · DOI: 10.1093/jxb/erae116 · Journal of Experimental Botany · 2024-05-20 ## TL;DR This paper discusses how a specific AMPK activator affects seed germination in rice by activating SnRK1. ## Contribution It identifies a specific AMPK activator that targets SnRK1 in rice, influencing germination. ## Key findings - AMPK activator 991 specifically activates SnRK1 in rice. - Activation of SnRK1 by the compound affects seed germination processes. - The study provides insights into metabolic regulation during germination. ## Abstract This article comments on: Hu Y, Lin Y, Bai J, Xu X, Wang Z, Ding C, Ding Y, Chen L. 2024. AMPK activator 991 specifically activates SnRK1 and thereby affects seed germination in rice. Journal of Experimental Botany 75, 2917–2932. ## Linked entities - **Proteins:** PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1), snRK1 (SNF1-related protein kinase) - **Chemicals:** AMPK activator 991 (PubChem CID 59267575) ## Full-text entities - **Genes:** APS2 (ADP-glucose pyrophosphorylase small subunit 2) [NCBI Gene 837066] {aka ADP-GLUCOSE PYROPHOSPHORYLASE, ADP-glucose pyrophosphorylase small subunit 2, F3F20.6, F3F20_6}, SUS2 (sucrose synthase 2) [NCBI Gene 834978] {aka ATSUS2, K21P3.6, K21P3_6, SSA, SUCROSE SYNTHASE, SUCROSE SYNTHASE FROM ARABIDOPSIS} - **Diseases:** metabolic diseases (MESH:D008659) - **Chemicals:** nitrogen (MESH:D009584), phosphopeptides (MESH:D010748), Compound 991 (-), T6P (MESH:C082722), AMP (MESH:D000249), carbohydrates (MESH:D002241), glucose (MESH:D005947), carbon (MESH:D002244), serine (MESH:D012694), starch (MESH:D013213) - **Species:** Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Arabidopsis thaliana (mouse-ear cress, species) [taxon 3702], Oryza sativa (Asian cultivated rice, species) [taxon 4530], Physcomitrium patens (species) [taxon 3218] - **Cell lines:** 35S-8 — Mus musculus (Mouse), Hybridoma (CVCL_CW33) ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11103107/full.md ## References 20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11103107/full.md --- Source: https://tomesphere.com/paper/PMC11103107