# Intracranial meningeal melanocytoma: a case report and literature review

**Authors:** Renuka Chintapalli

PMC · DOI: 10.1093/jscr/rjae332 · Journal of Surgical Case Reports · 2024-05-18

## TL;DR

A rare case of multiple brain melanocytomas in a young woman is reported, emphasizing imaging features that help diagnose these benign tumors before surgery.

## Contribution

The paper presents a rare case of multiple primary intracranial melanocytomas and highlights specific neuroimaging features useful for diagnosis.

## Key findings

- The patient had two melanocytoma lesions in the brain, confirmed by histopathology after surgery.
- Imaging showed a diffusely increased T1 signal without enhancement, aiding in preoperative diagnosis.
- This case underscores the importance of imaging in evaluating rare intracranial melanocytomas.

## Abstract

Primary intracranial melanocytoma is an uncommon benign pigmented tumor arising from leptomeningeal melanocytes. Neuroimaging characteristics of central nervous system melanocytoma are distinct from similarly presenting intracranial neoplasms and can aid in diagnosis prior to histopathological examination. In rare cases, there may be more than one lesion present. We report a case of a 19-year-old woman presenting with progressively worsening headaches, nausea, emesis, and generalized weakness of 2 months. Imaging revealed tumors in the parietal and ipsilateral medial temporal lobe. The patient underwent gross total resection of the parietal lesion which histopathological assessment revealed to be primary intracranial meningeal melanocytoma. This case highlights the utility of specific imaging criteria such as diffusely increased T1 signal without enhancement in the initial diagnostic evaluation of intracranial melanocytoma. We also describe the clinical characteristics, management strategy, and histopathological features of a rare case of a patient with multiple primary intracranial melanocytoma lesions.

## Full-text entities

- **Diseases:** headaches (MESH:D006261), lesion (MESH:D009059), emesis (MESH:D014839), Intracranial meningeal melanocytoma (MESH:D008577), weakness (MESH:D018908), benign pigmented tumor (MESH:D009369), Primary intracranial melanocytoma (MESH:D020765), intracranial melanocytoma (MESH:D001932), nausea (MESH:D009325), central nervous system melanocytoma (MESH:D002493)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11102787/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11102787/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11102787/full.md

---
Source: https://tomesphere.com/paper/PMC11102787