# Primary Rifampicin Mono-Resistant Tuberculosis of the Cervical, Mediastinal, and Axillary Lymphadenopathy in an Indian Male: A First-of-Its-Type Case

## TL;DR

A 27-year-old Indian man was diagnosed with a rare form of tuberculosis resistant to rifampicin, affecting multiple lymph node regions without lung involvement.

## Contribution

This is the first reported case of primary rifampicin-resistant extrapulmonary tuberculosis in multiple lymph node regions in an immunocompetent individual.

## Key findings

- The patient had no prior TB history and was immunocompetent.
- TB was confirmed via radiometric and nucleic acid amplification tests on lymph node samples.
- The case highlights the need for early detection of drug-resistant TB in extrapulmonary settings.

## Abstract

Tuberculosis is common in endemic countries. However, extrapulmonary tuberculosis is relatively rare, and primary extrapulmonary rifampicin mono-resistant tuberculosis of the cervical, mediastinal, and axillary lymph nodes simultaneously without pulmonary focus in an immunocompetent male has never been reported. Herein is a case of a 27-year-old Indian male with no previous history of tuberculosis who was diagnosed after an extensive clinical assessment with a radiometric and cartridge-based nucleic acid amplification assay of the swollen lymph nodes. He was put on antituberculous treatment per the all-oral longer regimen of the national program.