# Do not stumble over the same “stone” twice: a case series of endogenous endophthalmitis secondary to severe systemic diseases

## TL;DR

This paper reports three cases of eye infections caused by severe systemic diseases, emphasizing the importance of quick diagnosis and treatment to prevent vision loss.

## Contribution

The novelty lies in presenting a case series linking endogenous endophthalmitis to diverse systemic conditions and highlighting timely treatment outcomes.

## Key findings

- Prompt diagnosis and treatment of endogenous endophthalmitis can preserve vision.
- Eye symptoms were the initial signs in patients with underlying systemic diseases.
- Follow-up showed variable visual outcomes, including light perception and corrected vision.

## Abstract

Endogenous endophthalmitis (EE) is a rare but highly destructive eye emergency secondary to systemic infection. Acute endophthalmitis can lead to irreversible vision impairment or even loss of the whole eye, unless being diagnosed and treated promptly.

This study reports three typical EE cases of endogenous endophthalmitis secondary to different severe systemic diseases. Patients were recruited from the Department of ophthalmology at Zhongnan hospital of Wuhan University and the Department of ophthalmology at the Second Affiliated Hospital of Fujian Medical University. Patients were followed up for up to 60 days. Among these cases, the eye symptoms is the initial manifestations while secondary to original different special systemic conditions. Patients have been treated under dynamically prompt response undergoing systemic treatment and eye treatment at the same time. Best corrected visual acuity were 20/40, 20/60 and light perception during follow-up evaluation.

Our observation suggest that prompt identification and treatment could save patients’ vision from EE.

The online version contains supplementary material available at 10.1186/s12886-024-03478-7.