# Five years of advances in electrochemical analysis of protein biomarkers in lung cancer: a systematic review

**Authors:** Matías Regiart, Martín A. Fernández-Baldo, Bernardino Alcázar Navarrete, Concepción Morales García, Beatriz Gómez, Gonzalo R. Tortella, Teresa Valero, Francisco Gabriel Ortega

PMC · DOI: 10.3389/fchem.2024.1390050 · Frontiers in Chemistry · 2024-05-03

## TL;DR

This paper reviews recent electrochemical methods for detecting lung cancer biomarkers, aiming to improve early diagnosis and treatment.

## Contribution

The paper provides a systematic review of electrochemical techniques for lung cancer biomarker detection in clinical samples.

## Key findings

- Electrochemical methods offer robust detection of lung cancer biomarkers.
- These methods reduce time, cost, and assay complexity in clinical settings.

## Abstract

Lung cancer is the leading cause of cancer death in both men and women. It represents a public health problem that must be addressed through the early detection of specific biomarkers and effective treatment. To address this critical issue, it is imperative to implement effective methodologies for specific biomarker detection of lung cancer in real clinical samples. Electrochemical methods, including microfluidic devices and biosensors, can obtain robust results that reduce time, cost, and assay complexity. This comprehensive review will explore specific studies, methodologies, and detection limits and contribute to the depth of the discussion, making it a valuable resource for researchers and clinicians interested in lung cancer diagnosis.

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** Lung cancer (MESH:D008175), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11099832/full.md

## References

72 references — full list in the complete paper: https://tomesphere.com/paper/PMC11099832/full.md

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Source: https://tomesphere.com/paper/PMC11099832