# Data on characteristics of simplicia, phytoconstituents, and antioxidant activity of Moringa oleifera leaves ethanol extract

## TL;DR

This study provides data on the quality, chemical composition, and antioxidant activity of Moringa oleifera leaves and their ethanol extract.

## Contribution

The paper presents a detailed chemical and pharmacological profile of Moringa oleifera leaves and their ethanol extract.

## Key findings

- Moringa oleifera leaves meet quality standards except for high ash content.
- The ethanol extract contains flavonoids, tannins, and steroids, with 39 phytoconstituents identified.
- The extract shows significant antioxidant activity with an IC50 of 1422.45 mg/kg.

## Abstract

The article reports data on the chemical and pharmacological characteristics of Moringa oleifera simplicia and ethanol extract consisting of water content, acid-insoluble ash content, microbial contamination, heavy metal contamination, phytochemical analysis, TLC analysis, chemical profiling using LC-MS/MS, and the antioxidant activity. The M. oleifera leaves simplicia meet quality standards, except for ash content that exceeds the specified standards. Qualitative phytochemistry indicates that the ethanol extract of M. oleifera leaves contains flavonoids, tannins, and steroids. In total of 39 phytoconstituents were tentatively identified; the top 10 active compounds with the highest relative abundance percentage (%) are 4-undecylbenzenesulfonic acid (4,83), apigetrin (3,34), quercetin-3β-D-glucoside (3,28), D-(-)-quinic acid (1,69), corchorifatty acid F (1,52), 4-hydroxybenzaldehyde (1,47), isopropylmalic acid (1,17), 13(S)-HOTrE (1,08), astragalin (0,99), and D-(+)-phenyllactic acid (0,70). The ethanol extract of M. oleifera leaves contained a total phenolic content 7728,02 mg/kg, total flavonoids as quercetin content 1,19%, and antioxidant activity IC50 1422,45 mg/kg.