# Symptoms of depression among outpatients with suspected COVID-19 in metropolitan Local Government Areas of Kaduna State, Nigeria

**Authors:** Gregory C. Umeh, Laurent Cleenwerck de Kiev, Jabani Mamza, Aliyu Atiku, Suleiman Mohammed, Dauda S. Hananiya, Moses Onoh, Habibu B. Yahaya, Basirat Adeoti, Rabiat T. Musa, Mutiu Adegbite, Sunday Audu, Jeremiah Daikwo, Neyu Iliyasu, Amina Mohammed Baloni, Ibrahim Jahun, Ibrahim Jahun, Ibrahim Jahun, Ibrahim Jahun

PMC · DOI: 10.1371/journal.pone.0288567 · PLOS ONE · 2024-05-16

## TL;DR

This study found that outpatients with suspected COVID-19 in Nigeria had higher rates of depression symptoms compared to those without respiratory symptoms.

## Contribution

The study provides new insights into the mental health impact of acute respiratory infections in a Nigerian context.

## Key findings

- Depression symptoms were more common in patients with ARI (19.6%) than in those without (14.4%).
- Respondents with ARI symptoms had a higher proportion in the mild depression risk category.
- No significant difference was found in moderate and high depression risk categories between ARI and non-ARI groups.

## Abstract

The novel SARS-CoV-2 virus that causes Coronavirus disease (COVID-19) has redefined global health and response to Acute Respiratory Infection (ARI). The outbreak of a cluster of influenza-like illnesses in Wuhan, China, has morphed into a pandemic in the last quarter of 2019, stretching from South East Asia to Europe, The Americas, Africa, and the Australian subcontinent. We evaluated the prevalence of depression among outpatients diagnosed with ARI.

We utilized a cross-sectional, observational design and investigated the prevalence of symptoms of depression among outpatients with ARI and described the characteristics of outpatients with ARI in Kaduna State.

The prevalence of symptoms of depression was 19.6% for respondents with symptoms of ARI and 14.4% for those without symptoms of ARI. On no risk of depression, we had a higher proportion of the respondents without symptoms of ARI (86%) than those with symptoms of depression (80%) (M = 318.4, SD = 29.62 case, and M = 344.0, SD = 14.2 control, r = 0.88, CI = 13.5 to 6.5, P = 0.000952). Likewise, in the category with mild risk of depression, respondents without symptoms of ARI were fewer (10%) than those with symptoms of depression (15%) (M = 58.4, SD = 26.0 case, and M = 42.1, SD = 12.7 control, r = 0.86, CI = 11.8 to 5.8, P = 0.0136. There was no significant difference between respondents with symptoms of ARI and without symptoms of ARI in the categories of moderate (M = 13.6, SD = 5.1 case, and M = 11.6, SD = 4.6 control, r = 0.87, CI = 2.3 to 2.1, P = 0.178) and high (M = 5.6, SD = 2.5 case, and M = 4.4, SD = 3.2 control, r = 0.61, CI = 1.2 to 1.5, P = 0.174) risk of depression.

Symptoms of depression were commoner among respondents who presented with symptoms of Acute Respiratory Infection (ARI) at the Outpatient Department (OPD). However, further explanatory research is needed to establish causality.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), influenza-like illnesses (MESH:D007251), Coronavirus disease (MESH:D018352), depression (MESH:D003866), ARI (MESH:D012141)

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC11098515/full.md

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Source: https://tomesphere.com/paper/PMC11098515