# Gigantic laryngeal schwannoma: A case report with literature review

**Authors:** Daniel Nguyen, Nyein Nyein Htun, Cary Johnson

PMC · DOI: 10.1177/20363613241255669 · 2024-05-15

## TL;DR

This paper reports a rare case of a large laryngeal schwannoma in a 69-year-old patient and emphasizes the importance of considering this diagnosis for laryngeal masses.

## Contribution

The novelty lies in presenting a case of a large schwannoma with detailed clinical and pathological findings, emphasizing its diagnostic significance.

## Key findings

- A 69-year-old patient presented with a 6.3 cm laryngeal schwannoma causing stridor and dysphagia.
- Histopathology and immunohistochemistry confirmed the schwannoma diagnosis after resection.
- The case highlights the need to consider schwannoma in the differential diagnosis of laryngeal masses.

## Abstract

Laryngeal schwannoma is a rare benign nerve sheath tumor that is slow growing. The diagnosis is made from a combination of clinical, radiological, and histopathological findings, and the main method of treatment is resection. We report a case of a 69-year-old presenting with a neck mass causing stridor, dysphagia, and orthopnea. CT of the neck showed an enhancing mass measuring 6.3 cm and extending superior to the larynx. Emergent tracheostomy and mass resection were performed, and histopathology and immunohistochemical findings were obtained from the specimen supporting schwannoma. In conclusion, while rare, schwannoma should always be considered as a differential diagnosis for a laryngeal mass. More studies are needed to assess the size and prognosis of the tumor.

## Linked entities

- **Diseases:** schwannoma (MONDO:0002546)

## Full-text entities

- **Diseases:** orthopnea (MESH:D004417), Laryngeal schwannoma (MESH:D009442), tumor (MESH:D009369), stridor (MESH:D012135), benign nerve sheath tumor (MESH:D018317), Gigantic laryngeal schwannoma (MESH:D005877), dysphagia (MESH:D003680), neck mass (MESH:D006258), laryngeal mass (MESH:C536030)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11097735/full.md

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Source: https://tomesphere.com/paper/PMC11097735