Expression of concern: Enhancement of anti-leukemic potential of 2-hydroxyphenyl-azo-2′-naphthol (HPAN) on MOLT-4 cells through conjugation with Cu(ii)
Tathagata Deb, Priya Kalyan Gopal, Durba Ganguly, Piyal Das, Mausumi Paul, Manju Bikash Saha, Santanu Paul, Saurabh Das
TL;DR
This paper addresses concerns about a study on improving the anti-leukemic effects of HPAN through copper conjugation on MOLT-4 cells.
Contribution
The paper raises an expression of concern regarding the validity of previously published findings on HPAN and copper conjugation.
Findings
The paper questions the reliability of the original study's results.
It highlights the need for further verification of the anti-leukemic potential claims.
Abstract
Expression of concern for ‘Enhancement of anti-leukemic potential of 2-hydroxyphenyl-azo-2′-naphthol (HPAN) on MOLT-4 cells through conjugation with Cu(ii)’ by Tathagata Deb et al., RSC Adv., 2014, 4, 18419–18430, https://doi.org/10.1039/C3RA44765K.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsSynthesis and Characterization of Heterocyclic Compounds · Synthesis and biological activity · Synthesis of Tetrazole Derivatives
RSC Advances is publishing this expression of concern to alert readers that we are presently unable to confirm the reliability of the data presented in the microscopic images in Fig 4 of this article.
The Royal Society of Chemistry has asked the affiliated institution (Gurudas College) to investigate this matter and confirm the integrity and reliability of the data in Fig. 4 of the paper. An expression of concern will continue to be associated with this manuscript until we receive information from the institution on this matter.
Signed: Laura Fisher, Executive Editor, RSC Advances
Date: 9th May 2024
Supplementary Material