# Non-cirrhotic Ascites: A Case of Severe Alcoholic Hepatitis

**Authors:** Mohamed A Ebrahim, Eli A Zaher, Parth Patel, Marwan K Ahmed, Kanwal Ahmed

PMC · DOI: 10.7759/cureus.58187 · 2024-04-13

## TL;DR

This case report describes a rare instance of ascites in a non-cirrhotic patient with severe alcoholic hepatitis, highlighting the complexity of the condition and the need for better treatments.

## Contribution

The case presents a rare occurrence of non-cirrhotic portal hypertension in severe alcoholic hepatitis, contributing to understanding its varied clinical manifestations.

## Key findings

- Ascites occurred in a non-cirrhotic patient with severe alcoholic hepatitis.
- Sinusoidal non-cirrhotic portal hypertension was identified as the underlying cause.
- Current treatments for AH show limited efficacy, suggesting a need for further research.

## Abstract

This case report presents a unique instance of ascites in acute alcoholic hepatitis (AH) occurring in a non-cirrhotic patient. Comprehensive diagnostic evaluation excluded alternative etiologies, pinpointing sinusoidal non-cirrhotic portal hypertension. Present therapeutic modalities for AH, including steroids and pentoxifylline, offer limited efficacy, necessitating ongoing investigation. Liver transplantation may be contemplated in refractory cases. This case underscores the intricate nature of AH presentations and the challenges in their management, emphasizing the imperative need for continued research to delineate optimal therapeutic strategies. Early intervention remains pivotal in addressing AH complications, underscoring the need for heightened clinical vigilance and proactive treatment approaches in such cases.

## Linked entities

- **Diseases:** alcoholic hepatitis (MONDO:0001505), portal hypertension (MONDO:0005080)

## Full-text entities

- **Diseases:** portal hypertension (MESH:D006975), cirrhotic (MESH:D000094724), acute alcoholic hepatitis (OMIM:610251), Ascites (MESH:D001201), AH (MESH:D006519)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11089831/full.md

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Source: https://tomesphere.com/paper/PMC11089831