# Secondary analysis of Staphylococcus aureus whole genomes reveals diverse antimicrobial resistance profiles

## TL;DR

This study analyzed Staphylococcus aureus genomes to identify diverse antimicrobial resistance genes across six strains.

## Contribution

The novel contribution is the identification of 75 unique resistance genes against 22 antimicrobial compounds in S. aureus strains.

## Key findings

- 75 unique antimicrobial resistance genes were predicted in six S. aureus strains.
- These genes confer resistance to 22 different antimicrobial compounds.
- The study used de novo genome assembly and annotation for resistance gene prediction.

## Abstract

Antimicrobial resistance (AMR) in microorganisms is an ongoing threat to human health across the globe. To better characterize the AMR profiles of six strains of
Staphylococcus aureus
, we performed a secondary analysis that consisted of the following steps: 1) download fastq files from the Sequence Read Archive, 2) perform a
de novo
genome assembly from the sequencing reads, 3) annotate the assembled contigs, 4) predict the presence of antimicrobial resistance genes. We predicted the presence of 75 unique genes that conferred resistance against 22 unique antimicrobial compounds.