# Doxycycline-Associated Ulcerative Esophagitis: A Report of a Rare Case

**Authors:** Kunal Priyadarshi, Suman Panda, Amiya Ranjan, Dheeraj Yadav, Zaid Nafe

PMC · DOI: 10.7759/cureus.58079 · 2024-04-11

## TL;DR

A rare case of esophageal injury caused by doxycycline is presented, emphasizing the importance of proper medication use and endoscopic evaluation.

## Contribution

The paper presents a rare clinical case linking doxycycline to ulcerative esophagitis and highlights diagnostic and management considerations.

## Key findings

- Doxycycline can cause ulcerative esophagitis in rare cases.
- Endoscopy is crucial for diagnosing medication-induced esophageal injury.
- Proper medication administration is essential to prevent such injuries.

## Abstract

This study addresses the risks of medication-induced esophageal injury through a case presentation of a 30-year-old patient treated with doxycycline. The case highlights the importance of proper medication administration and the role of endoscopic evaluation in diagnosis and management. The broader discussion emphasizes the prevalence of such injuries, especially with antibiotics, and factors influencing their occurrence. A clinical study illustrates the corrosive effect of tetracycline, highlighting the role of pH and hyperosmolar properties. The study concludes with a reminder of the critical role of healthcare professionals in recognizing and managing medication-induced esophagitis, with endoscopy as a key diagnostic tool.

## Linked entities

- **Chemicals:** doxycycline (PubChem CID 54671203), tetracycline (PubChem CID 54675776)

## Full-text entities

- **Diseases:** Ulcerative Esophagitis (MESH:D004941)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11088970/full.md

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Source: https://tomesphere.com/paper/PMC11088970