From No Disease to Stage IV Colon Cancer in Four Months: A Case Report

TL;DR

A 61-year-old woman developed stage IV colon cancer four months after starting steroid treatment for a rheumatologic condition, despite a recent clean colonoscopy.

Contribution

Highlights a potential link between corticosteroid use and rapid progression of colorectal cancer.

Findings

Patient developed metastatic colorectal cancer four months after starting glucocorticoid therapy.

Prior colonoscopy showed no signs of cancer, suggesting rapid disease progression.

Case raises awareness about the possible role of corticosteroids in accelerating cancer development.

Abstract

Colorectal cancer remains one of the most common cancers in the population. Meanwhile, steroids or other immunosuppressive drugs are usually given in rheumatological diseases as a treatment for flare-ups. Herein, we present the case of a 61-year-old female diagnosed with metastatic colorectal cancer merely four months following the commencement of glucocorticoid therapy for a recently diagnosed rheumatologic condition, despite a clear colorectal cancer screening colonoscopy conducted four months prior. The case report discusses the possible impact of corticosteroids on the fast disease progression of colorectal cancer and raises awareness regarding this potential risk.

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