# Unsolved Controversies in Management of Infective Endocarditis

**Authors:** Rima Othman, Hassan H Mallat, Raed Osman, Ahmad Ayoubi

PMC · DOI: 10.7759/cureus.58095 · 2024-04-12

## TL;DR

This paper discusses a case of a young patient with infective endocarditis, highlighting the disease's severity and the need for prompt, multidisciplinary care.

## Contribution

The paper presents a rare case of subacute infective endocarditis in a previously healthy young adult.

## Key findings

- Infective endocarditis can occur in young, previously healthy individuals.
- A multidisciplinary approach is crucial for managing IE due to its high mortality.
- The case highlights the importance of recognizing IE in atypical presentations.

## Abstract

Infective endocarditis (IE) is defined as an infection in the cardiac endothelium. It is triggered by both bacteremia and endothelial dysfunction and poses many risks to the health of the patient. Many organisms can cause IE with Staphylococcus aureus being the major cause. Signs and symptoms may vary according to age and agent but almost all cases are presented with fever, fatigue, and a maculopapular rash. Although pediatric IE is very rare, risk factors such as congenital heart defects have been identified, with some of the cases remaining a mystery. We present a case of a 19-year-old patient, previously healthy and developing subacute IE with sepsis and septic embolic showers in multiple organs. IE cannot be taken for granted as mortality is high, hence a multidisciplinary approach is prompt and necessary for the survival of the patient.

## Linked entities

- **Diseases:** infective endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** sepsis (MESH:D018805), bacteremia (MESH:D016470), congenital heart defects (MESH:D006330), IE (MESH:D004696), fever (MESH:D005334), fatigue (MESH:D005221), infection (MESH:D007239), maculopapular rash (MESH:D005076), dysfunction (MESH:D006331)
- **Species:** Staphylococcus aureus (species) [taxon 1280], Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11088747/full.md

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Source: https://tomesphere.com/paper/PMC11088747