# Jaundice and Higher Procalcitonin Level Revealing a Small-Cell Lung Cancer With Pancreatic Metastasis: A Case Report From Eastern Morocco

**Authors:** Hind Chibani, Soufia El Ouardani, Mouhsine Omari, Karich Nassira, Ouissam Al Jarroudi, Hanane Hadj Kacem, Sami Aziz Brahmi, Amal Bennani, Said Afqir

PMC · DOI: 10.7759/cureus.58041 · 2024-04-11

## TL;DR

A rare case of small-cell lung cancer with pancreatic metastasis and high procalcitonin levels is reported, highlighting diagnostic challenges and treatment response.

## Contribution

This case report presents a rare combination of jaundice, high procalcitonin, and pancreatic metastasis in small-cell lung cancer.

## Key findings

- Pancreatic metastasis in SCLC is uncommon and challenging to diagnose.
- The patient showed a significant response to platinum-based chemotherapy.
- Procalcitonin may be a marker of paraneoplastic syndrome in this context.

## Abstract

Small-cell lung cancer (SCLC) is highly aggressive, with a severe tendency for metastasis. Pancreatic metastasis in SCLC is uncommon, also jaundice as a major symptom of small-cell lung cancer is even rarer. The diagnosis of pancreatic metastasis is a real challenge for the medical team, it relies on both radiological and pathological details. We report a case of a 58-year-old male admitted for SCLC with pancreatic metastasis and a higher level of procalcitonin. He received platinum-based chemotherapy with a swell response. The focus of this study will be on the characteristics of pancreatic metastasis, along with their diagnosis and treatment approaches. Procalcitonin as a paraneoplastic syndrome will also be discussed in this study.

## Linked entities

- **Diseases:** small-cell lung cancer (MONDO:0008433)

## Full-text entities

- **Diseases:** SCLC (MESH:D055752), Pancreatic Metastasis (MESH:D009362), Jaundice (MESH:D007565), paraneoplastic syndrome (MESH:D010257)
- **Chemicals:** platinum (MESH:D010984)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11088360/full.md

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Source: https://tomesphere.com/paper/PMC11088360