Retraction of: PHTF2 regulates lipids metabolism in gastric cancer
Yuhua Chi, Haiyan Wang, Fengsong Wang, Mingcui Ding
Abstract
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TopicsCancer, Lipids, and Metabolism · Cancer, Hypoxia, and Metabolism · Peroxisome Proliferator-Activated Receptors
This article has been retracted: Aging has completed its investigation of this paper. We found that the immunohistochemistry images in Figure 2H, showing PHTF2 expression pattern in gastric cancer tissues, were previously published in an unrelated paper from a different lab studying PBX1 protein in clear cell renal carcinoma [1]. We also found that the image of immunofluorescence staining in Figure 3I, representing the neutral lipids content detected by double staining with BODIPY 493/503 dye in GCIY/shACSL1 gastric cancer cells, is a duplication of a BODIPY image of Zebrafish liver cells from an unrelated paper [2]. In addition, the colony formation images shown in Figure 4B are the same as in an earlier published paper from an unrelated team of authors studying bladder cancer [3]. The authors were informed about the results of the Aging investigation and all authors agreed that the article should be retracted.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Wei X, Yu L, Li Y. PBX 1 promotes the cell proliferation via JAK 2/STAT 3 signaling in clear cell renal carcinoma. Biochem Biophys Res Commun. 2018; 500:650–57. 10.1016/j.bbrc.2018.04.12729678569 · doi ↗ · pubmed ↗
- 2Wang J, Han SL, Lu DL, Li LY, Limbu SM, Li DL, Zhang ML, Du ZY. Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells. Front Physiol. 2019; 10:1077. 10.3389/fphys.2019.0107731496957 PMC 6713122 · doi ↗ · pubmed ↗
- 3Li Y, Zhang X, Zhou X, Zhang X. LHPP suppresses bladder cancer cell proliferation and growth via inactivating AKT/p 65 signaling pathway. Biosci Rep. 2019; 39:BSR 20182270. 10.1042/BSR 2018227031262971 PMC 6667728 · doi ↗ · pubmed ↗