Thymol, a Monoterpenoid within Polymeric Iodophor Formulations and Their Antimicrobial Activities
Zehra Edis, Samir Haj Bloukh
TL;DR
This study explores a new antimicrobial formulation combining thymol, iodine, and aloe vera to combat drug-resistant microbes.
Contribution
The paper introduces a novel polymeric iodophor formulation with thymol and aloe vera showing strong antimicrobial activity.
Findings
The formulation showed potent antifungal and antibacterial effects against 10 reference strains.
Strong inhibitory action was observed on surgical sutures, cotton bandages, and face masks.
The formulation is proposed as a potential wound infection treatment and contact-killing spray.
Abstract
Antimicrobial resistance (AMR) poses an emanating threat to humanity’s future. The effectiveness of commonly used antibiotics against microbial infections is declining at an alarming rate. As a result, morbidity and mortality rates are soaring, particularly among immunocompromised populations. Exploring alternative solutions, such as medicinal plants and iodine, shows promise in combating resistant pathogens. Such antimicrobials could effectively inhibit microbial proliferation through synergistic combinations. In our study, we prepared a formulation consisting of Aloe barbadensis Miller (AV), Thymol, iodine (I2), and polyvinylpyrrolidone (PVP). Various analytical methods including SEM/EDS, UV-vis, Raman, FTIR, and XRD were carried out to verify the purity, composition, and morphology of AV-PVP-Thymol-I2. We evaluated the inhibitory effects of this formulation against 10 selected…
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Taxonomy
TopicsComputability, Logic, AI Algorithms