# Influence of Laser Treatment of Ti6Al4V on the Behavior of Biological Cells

## TL;DR

This study examines how laser treatment of Ti6Al4V affects cell behavior, suggesting it could improve dental implants by enhancing surface properties for better cell adhesion.

## Contribution

The novel contribution is demonstrating how laser treatment can modify Ti6Al4V surfaces to influence biological cell colonization and orientation.

## Key findings

- Laser treatment of Ti6Al4V increases the active surface area for cell adhesion.
- Modified surfaces show potential for guiding cell orientation during growth.
- No conclusive correlation was found between wettability and biocompatibility.

## Abstract

This article explores the enhancement of material surface properties of Ti6Al4V, potentially applicable to dental implants, through ultra-short pulse laser systems. This study investigates potential connections between surface wettability and biocompatibility, addressing the challenge of improving variability in material properties with specific laser treatment. Several designed microstructures were manufactured using a picosecond laser system. After that, the wettability of these structures was measured using the sessile drop method. The basic behavior and growth activity of biological cells (MG-63 cell line) on treated surfaces were also analyzed. While the conducted tests did not conclusively establish correlations between wettability and biocompatibility, the results indicated that laser treatment of Ti6Al4V could effectively enlarge the active surface to better biological cell colonization and adhesion and provide a focused moving orientation. This outcome suggests the potential application of laser treatment in producing special dental implants to mitigate the issues during and following implantation.