# A Rare Case of Rapid Lymphadenopathy Progression in Hodgkin’s Lymphoma: A Case Report

**Authors:** Harsh Bhalala, Yacoub Faroun, Wenxin Liao

PMC · DOI: 10.7759/cureus.57954 · Cureus · 2024-04-10

## TL;DR

A 30-year-old man developed Hodgkin’s lymphoma with lymph node swelling that appeared suddenly within an hour, highlighting the need for quick diagnosis in unusual cases.

## Contribution

This case report presents a rare instance of rapid lymphadenopathy in Hodgkin’s lymphoma, expanding the known clinical presentation of the disease.

## Key findings

- A 30-year-old male experienced sudden lymph node swelling within an hour, a rare presentation for Hodgkin’s lymphoma.
- The case highlights the importance of prompt investigation for atypical symptoms to ensure timely diagnosis and treatment.
- The patient’s lymphadenopathy remained stable after the initial rapid onset, leading to a confirmed diagnosis of Hodgkin’s lymphoma.

## Abstract

Hodgkin’s lymphoma is a B-cell neoplasm that typically manifests with gradual lymphadenopathy progression over weeks to months. However, we present an exceptional case of Hodgkin’s lymphoma marked by an unusually rapid development of lymphadenopathy within an hour. A 30-year-old male presented with a left neck swelling that occurred within an hour and then remained stable in size for three days, prompting an investigation revealing widespread lymphadenopathy consistent with Hodgkin’s lymphoma. This case outlines the importance of recognizing and investigating unusual presentations of Hodgkin’s lymphoma promptly, emphasizing the necessity for expedited diagnosis and intervention.

## Linked entities

- **Diseases:** Hodgkin’s lymphoma (MONDO:0004952)

## Full-text entities

- **Diseases:** Hodgkin's Lymphoma (MESH:D006689), neck swelling (MESH:D006258), B-cell neoplasm (MESH:D016393), Lymphadenopathy (MESH:D008206)

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11083759/full.md

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Source: https://tomesphere.com/paper/PMC11083759