# Chameleonic Chloroma: A Case of Myeloid Sarcoma Presenting as a Pancreatic Head Mass

## TL;DR

A rare case of pancreatic myeloid sarcoma, a type of acute myeloid leukemia, was diagnosed in a young man after initial tests were unclear.

## Contribution

This case highlights the diagnostic difficulty of pancreatic myeloid sarcoma when it occurs without prior blood cancer.

## Key findings

- Pancreatic myeloid sarcoma can present without a prior hematologic malignancy.
- Endoscopic biopsies and bone marrow analysis were crucial for confirming the diagnosis.
- Such cases are rare and often challenging to identify initially.

## Abstract

We report a case of pancreatic myeloid sarcoma (MS), an extremely rare manifestation of acute myeloid leukemia (AML), in a 35-year-old male who presented with epigastric pain and watery stools. Initial diagnostic testing was inconclusive; however, following an extensive evaluation, endoscopic biopsies suggested AML, which was confirmed by a bone marrow biopsy. Given that few cases are documented in the literature, pancreatic MS without a preexisting hematologic malignancy poses a significant diagnostic challenge.