# Introduction to ‘Medicinal Chemistry Small Molecule Probes’

**Authors:** Gemma Nixon, Khondaker Miraz Rahman, John Spencer

PMC · DOI: 10.1039/d4cb90005g · RSC Chemical Biology · 2024-03-25

## TL;DR

This paper introduces a collection of research on small molecule probes used in medicinal chemistry.

## Contribution

The paper highlights new insights and developments in small molecule probe research.

## Key findings

- The themed collection showcases recent advancements in medicinal chemistry probes.
- It provides a platform for researchers to share innovative probe designs and applications.

## Abstract

Gemma Nixon, Khondaker Miraz Rahman and John Spencer introduce the RSC Chemical Biology themed collection on ‘Medicinal Chemistry Small Molecule Probes’.

## Full-text entities

- **Genes:** USP30 (ubiquitin specific peptidase 30) [NCBI Gene 84749], HDAC9 (histone deacetylase 9) [NCBI Gene 9734] {aka HD7, HD7b, HD9, HDAC, HDAC7B, HDAC9B}, KDM8 (lysine demethylase 8) [NCBI Gene 79831] {aka JMJD5}
- **Diseases:** gliomas (MESH:D005910), viral infections (MESH:D014777), toxicity (MESH:D064420), cystic fibrosis (MESH:D003550), bacterial infections (MESH:D001424), coronavirus infections (MESH:D018352), brain cancers (MESH:D001932), malaria (MESH:D008288), influenza (MESH:D007251), covid (MESH:D000086382)
- **Chemicals:** artemisinin (MESH:C031327), Sialic acids (MESH:D012794), lysine (MESH:D008239), cyanopyrolidine (-), ATP (MESH:D000255), Temozolomide (MESH:D000077204), cysteine (MESH:D003545), sugar (MESH:D000073893), tyrosine (MESH:D014443)
- **Species:** Homo sapiens (human, species) [taxon 9606], Pseudomonas aeruginosa (species) [taxon 287]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11078211/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11078211/full.md

---
Source: https://tomesphere.com/paper/PMC11078211