# Breast cancer insights from Northern Israel: a comprehensive analysis of survival rates among Jewish and Arab women

**Authors:** Omar Badran, Salvatore Campisi-Pinto, Mahmoud Abu Amna, Ilit Turgeman, Samih Yosef, Gil Bar-Sela

PMC · DOI: 10.3389/fonc.2024.1337521 · Frontiers in Oncology · 2024-04-24

## TL;DR

This study examines breast cancer survival rates in northern Israel from 2000 to 2022, finding that socioeconomic status, age, and comorbidities significantly affect outcomes.

## Contribution

The study provides new insights into how socioeconomic status and age influence breast cancer survival in a diverse population in northern Israel.

## Key findings

- Socioeconomic status significantly improves survival rates (OR 2.50).
- Younger patients diagnosed recently show improved five-year survival (90.7%).
- Higher Charlson Comorbidity Index scores correlate with lower survival rates.

## Abstract

This study investigates breast cancer survival rates between 2000 and 2022 in northern Israel, focusing on ethnicity, socioeconomic status, age at diagnosis, and the Charlson Comorbidity Index. Analyzing data from Clalit Health Services, we studied 8,431 breast cancer patients (6,395 Jewish, 2,036 Arab). We compared five- and ten-year survival rates across different demographics. Ethnicity showed a minor impact on survival (OR 1.12, 95% CI: 0.93 - 1.35). Socioeconomic status had a significant effect, with a higher level of improving survival (OR 2.50, 95% CI: 2.04 – 3.08). Age was crucial; women 18-39 had better survival than 60-100, but no significant difference was found between the 18-39 and 40-59 age groups [OR (CI 0.90 – 1.53, p = 0.231)]. For the Charlson Comorbidity Index, women with scores of 3-10 showed lower survival compared to scores of 0 and 1-2. There was a notable improvement in five-year survival rates among patients aged 18-59 diagnosed from 2009-2018 (90.7%) compared to 2000-2008 (86.9%) (p = 0.0046), but not in patients aged 60-100. The study highlights that socioeconomic status, age, and comorbidity scores are significant in determining survival rates for breast cancer. The improvement in survival rates for younger patients diagnosed more recently reflects advancements in treatment and care. This research provides valuable insights into the factors affecting breast cancer survival rates, underscoring the role of socioeconomic status, age, and comorbidities while also highlighting the progress in breast cancer treatment over recent years.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** Breast cancer (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

59 references — full list in the complete paper: https://tomesphere.com/paper/PMC11076725/full.md

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Source: https://tomesphere.com/paper/PMC11076725