# Pyoderma Gangrenosum: A Case Highlighting the Importance of Timely Diagnosis

**Authors:** Rabia Rukhshan, Chioma Eliogu, Anuja Mistry, Simran Brar, Arshad Ali Mohd, Lela Ruck

PMC · DOI: 10.7759/cureus.57762 · Cureus · 2024-04-07

## TL;DR

A case of Pyoderma Gangrenosum shows how delayed diagnosis can lead to severe outcomes, emphasizing the need for early recognition.

## Contribution

This case highlights the importance of timely diagnosis in managing Pyoderma Gangrenosum to prevent severe complications.

## Key findings

- The patient's condition was misdiagnosed as recurrent cellulitis for a long time.
- A biopsy confirmed Pyoderma Gangrenosum after multiple emergency visits.
- The patient underwent amputation due to delayed appropriate treatment.

## Abstract

Pyoderma Gangrenosum (PG) is a distinctive dermatologic condition characterized by recurrent inflammatory ulcers, often manifesting with violaceous borders and undermined edges. We describe a 40-year-old male who presented with acute on chronic necrotic ulcer of the left index finger following foreign body penetration. Despite multiple emergency department visits and treatments for presumed recurrent cellulitis, including various debridements, his condition persisted without symptomatic relief. A high index of clinical suspicion, due to recurrent presentations and potential pathergy, prompted an excision biopsy which confirmed Pyoderma Gangrenosum (PG). Regrettably, due to delays in appropriate management, the patient chose amputation because of intolerable pain, highlighting the critical importance of timely diagnosis for optimal patient outcomes.

## Linked entities

- **Diseases:** Pyoderma Gangrenosum (MONDO:0018824), cellulitis (MONDO:0005230)

## Full-text entities

- **Diseases:** cellulitis (MESH:D002481), inflammatory (MESH:D007249), PG (MESH:D017511), necrotic ulcer (MESH:D014456), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11075739/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11075739/full.md

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Source: https://tomesphere.com/paper/PMC11075739