# Beyond Excision: Cryotherapy as a Non-surgical Treatment for Palatal Solitary Neurofibroma

## TL;DR

Cryotherapy successfully treated a rare palatal neurofibroma without surgery, offering a non-invasive alternative.

## Contribution

This case is the first to demonstrate liquid nitrogen cryotherapy as an effective non-surgical treatment for palatal solitary neurofibroma.

## Key findings

- Cryotherapy resolved a palatal solitary neurofibroma in four sessions with no recurrence after five months.
- Liquid nitrogen cryotherapy is a viable non-surgical alternative for treating palatal solitary neurofibromas.

## Abstract

Palatal solitary neurofibromas (SNFs), not linked to neurofibromatosis type 1, are uncommon. A 45-year-old female with a palatal SNF underwent non-surgical treatment using liquid nitrogen cryotherapy (LNC). The lesion, initially 9 x 8 x 3 mm, was treated with two 1-2 minute freeze-thaw cycles, progressively extended to two 2-2 minute freeze-thaw cycles to address the refractoriness. After four LNC sessions, the lesion resolved without recurrence at five months. This case demonstrates LNC’s efficacy as a surgical alternative for palatal SNF, offering a non-invasive option for patients declining surgery. The positive outcome warrants further research into LNC’s role in managing similar benign lesions.