# Unraveling the Complexity: Ehrlichiosis-Induced Septic Shock and Acute Respiratory Distress Syndrome

**Authors:** Anshu Kataria, Anne M Arcidiacono, Minhaz Murshad, Shuvendu Sen, Ahmad A Homoud

PMC · DOI: 10.7759/cureus.57682 · Cureus · 2024-04-05

## TL;DR

A 67-year-old man developed severe ehrlichiosis leading to septic shock and ARDS, but recovered after doxycycline treatment.

## Contribution

This case highlights the rare severity of ehrlichiosis and effective management strategies using doxycycline.

## Key findings

- Prompt treatment with doxycycline led to full recovery from severe ehrlichiosis.
- Ehrlichia chaffeensis infection was identified as the cause of septic shock and ARDS in an immunocompetent patient.

## Abstract

Human monocytic ehrlichiosis typically presents with nonspecific cold-like symptoms and a history of recent tick exposure, often responding well to early treatment. Here, we present the case of a 67-year-old immunocompetent male who initially presented with fevers, chills, dysuria, and hematuria, leading to admission to the intensive care unit with septic shock and acute respiratory distress syndrome (ARDS), which was later attributed to Ehrlichia chaffeensis infection. Prompt treatment with doxycycline resulted in a full clinical recovery. This case highlights the rare occurrence of severe ehrlichiosis and provides insights into its effective management based on updated literature.

## Linked entities

- **Chemicals:** doxycycline (PubChem CID 54671203)
- **Diseases:** ehrlichiosis (MONDO:0016003), acute respiratory distress syndrome (MONDO:0006502)

## Full-text entities

- **Diseases:** Septic Shock (MESH:D012772), dysuria (MESH:D053159), fevers (MESH:D005334), chills (MESH:D023341), hematuria (MESH:D006417), ARDS (MESH:D012128), Ehrlichia chaffeensis infection (MESH:D016873)
- **Chemicals:** doxycycline (MESH:D004318)

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11070192/full.md

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Source: https://tomesphere.com/paper/PMC11070192