# A Rare Case of Renal Vein Thrombosis Secondary to Oral Contraceptive Pills

**Authors:** Lavneet Chawla, Amitoj S Sachdeva

PMC · DOI: 10.7759/cureus.57604 · Cureus · 2024-04-04

## TL;DR

A 29-year-old woman developed kidney vein blood clots likely due to birth control pills, highlighting the need to consider this risk factor.

## Contribution

This case report highlights the rare but important link between oral contraceptive use and renal vein thrombosis.

## Key findings

- A 29-year-old female with oral contraceptive use developed unilateral renal vein thrombosis.
- Discontinuation of oral contraceptives and anticoagulation therapy led to symptom improvement.
- The case emphasizes oral contraceptives as a risk factor for venous thromboembolism.

## Abstract

Renal vein thrombosis (RVT) is a common complication of nephrotic syndrome and renal malignancy. However, its association with oral contraceptive use has rarely been reported. We report a case of a 29-year-old female with a history of oral contraceptive use, presenting with acute flank pain. On further investigation, she was found to have unilateral RVT. Oral contraception was discontinued, and she was started on therapeutic anticoagulation, initially with low-molecular-weight heparin, and then switched to apixaban. Her symptoms improved, and she is currently doing well. This case signifies the importance of proper history-taking and how oral contraception should be considered a significant risk factor for venous thromboembolism.

## Linked entities

- **Chemicals:** apixaban (PubChem CID 10182969)
- **Diseases:** venous thromboembolism (MONDO:0005399)

## Full-text entities

- **Diseases:** flank pain (MESH:D021501), nephrotic syndrome (MESH:D009404), venous thromboembolism (MESH:D054556), RVT (MESH:D012170), renal malignancy (MESH:D009369)
- **Chemicals:** apixaban (MESH:C522181), Oral contraception (-), low-molecular-weight heparin (MESH:D006495)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11069633/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11069633/full.md

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Source: https://tomesphere.com/paper/PMC11069633