# Salvage surgery for pouch-related complication after ileal pouch–anal anastomosis: a report of two cases

**Authors:** Yusuke Izutani, Takayuki Ogino, Yuki Sekido, Mitsunobu Takeda, Tsuyoshi Hata, Atsushi Hamabe, Norikatsu Miyoshi, Mamoru Uemura, Tsunekazu Mizushima, Yuichiro Doki, Hidetoshi Eguchi

PMC · DOI: 10.1186/s40792-024-01910-0 · Surgical Case Reports · 2024-05-03

## TL;DR

This paper reports two cases where salvage surgery was needed to treat severe complications after a surgical procedure for ulcerative colitis.

## Contribution

The paper presents two clinical cases where salvage surgery was necessary due to persistent complications after ileal pouch–anal anastomosis.

## Key findings

- Salvage surgery was required in two patients with persistent pelvic abscesses and fistulas after ileal pouch–anal anastomosis.
- Both patients had complications that did not improve with seton drainage or ileostomy reconstruction.
- Post-surgery, both patients successfully reintegrated into society.

## Abstract

Pouch-related complications (PRCs), such as pelvic abscesses and perianal complex fistulas, can occur after ileal pouch–anal anastomosis (IPAA) in ulcerative colitis (UC). They are often difficult to treat and require salvage surgery. We report two cases of PRC associated with fistulas.

First case: A 38-year-old man was diagnosed with UC at age 26 years. Four months after the diagnosis of UC, the patient underwent hand-assisted laparoscopic restorative proctocolectomy, IPAA, and ileostomy for acute fulminant UC. Two years after the closure of the ileostomy, the patient developed a perianal abscess and underwent ileostomy reconstruction. He was referred to our department at 35 years of age, because his symptoms did not improve despite repeated seton drainage of a complicated perineal fistula. We diagnosed PRC with a pelvic abscess and complicated pouch fistula and performed salvage surgery. This diagnosis was revised to Crohn’s disease. Second case: A 50-year-old man was diagnosed with UC at age 18 years and was administered high doses of steroids; however, his symptoms did not improve. He underwent restorative proctocolectomy, IPAA, and ileostomy at another hospital. The ileostomy was closed, and his condition stabilized thereafter. At 35 years of age, perianal pain developed, and he was diagnosed with a complicated pouch–perineal fistula. A fistula was observed near the staple line of the ileal end closure on the head side of the pouch. Reconstruction of the ileostomy and seton drainage were performed; however, his symptoms did not improve, and he was referred to our hospital. We diagnosed PRC with a pelvic abscess and a complicated pouch fistula and performed salvage surgery. The resected specimen showed strictures in two locations: at the oral site of the afferent limb (at the pouch) and at the IPAA. Both patients returned to society and are currently outpatients.

We encountered two cases of PRC after IPAA that did not improve with seton drainage or ileostomy. Pouch resection was performed after considering the patient’s quality of life and reintegration into society.

## Linked entities

- **Diseases:** ulcerative colitis (MONDO:0005101), Crohn’s disease (MONDO:0005011)

## Full-text entities

- **Diseases:** PRCs (MESH:D048909), pelvic abscess (MESH:D000038), fistula (MESH:D005402), perianal pain (MESH:D010146), Pouch (MESH:D004062), UC (MESH:D003093), pouch-perineal fistula (MESH:D009437), SECOND (MESH:D016609), Crohn's disease (MESH:D003424)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11068705/full.md

## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC11068705/full.md

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Source: https://tomesphere.com/paper/PMC11068705