# Success in Parenthood: The In Vitro Maturation Breakthrough in Infertility

**Authors:** Namrata Choudhary, Jarul Shrivastava, Akash More, Ashish Anjankar, Deepti Shrivastava

PMC · DOI: 10.7759/cureus.57486 · 2024-04-02

## TL;DR

A couple with infertility issues successfully underwent a treatment involving in vitro maturation of eggs to avoid complications from ovarian stimulation.

## Contribution

The case report highlights the use of in vitro maturation as a safer alternative for PCOS patients to prevent OHSS.

## Key findings

- In vitro maturation of immature oocytes was successfully used in a PCOS patient.
- The treatment minimized the risk of ovarian hyperstimulation syndrome.
- Cryopreservation of embryos was achieved through ICSI following IVM.

## Abstract

This case report revolves around a 37-year-old woman and her 39-year-old husband, who have been married for seven years and were seeking treatment for infertility. The husband has been diagnosed with asthenozoospermia for the past six years and has been on continued medication, and the woman has been diagnosed with polycystic ovarian syndrome (PCOS). To improve fertility outcomes, this case report enlightens the treatment and medical strategy for people with PCOS. Treatment included low-dose ovarian stimulation for the removal of immature eggs, and then in vitro maturation (IVM) of those oocytes was done. Later, intracytoplasmic sperm injection (ICSI) was performed to form the blast. The formed blasts were later cryopreserved till embryo transfer. This case report highlights the importance of preventing the risk of ovarian hyperstimulation syndrome (OHSS) in patients with PCOS.

## Linked entities

- **Diseases:** ovarian hyperstimulation syndrome (MONDO:0011972)

## Full-text entities

- **Diseases:** Infertility (MESH:D007246), OHSS (MESH:D016471), PCOS (MESH:D011085), asthenozoospermia (MESH:D053627)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11066372/full.md

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Source: https://tomesphere.com/paper/PMC11066372