# Knowledge, Attitudes, and Perceptions of Skin Cancer Clinical Trials in the Hispanic Population

## TL;DR

This study explores why Hispanic patients are underrepresented in skin cancer clinical trials and finds they are more likely to agree with statements about the benefits of participation.

## Contribution

The study identifies specific motivational factors unique to the Hispanic population for participating in skin cancer clinical trials.

## Key findings

- Hispanic patients showed stronger agreement with statements about the benefits of clinical trials for their community.
- Hispanic ethnicity was linked to higher odds of agreeing that participation in skin cancer studies is beneficial.
- Hispanic patients were more likely to express a desire to help others through trial participation.

## Abstract

Objective: To determine the factors that might limit Hispanic patients from participating in dermatological clinical trials.

Methods: From January 2022 to July 2022, we administered a 31-item, in-person questionnaire to patients recruited in the waiting area of the Caridad Center, one of the largest free clinics in the United States with a predominately Hispanic population, and a nearby private primary care clinic.

Results: Overall, Hispanic patients agreed significantly more with statements in the domain of attitude and behavioral beliefs compared to non-Hispanic survey respondents. The Hispanic ethnicity was associated with increased odds of agreeing with the following statements: “My community would really benefit from skin cancer clinical trials” (OR=0.52; 95% CI 0.30, 0.92), “My participation in a skin cancer study would be very good” (OR=0.59; 95% CI 0.35, 0.99), and “I like to do good for others” (OR=0.41; 95% CI 0.22, 0.77).

Conclusion: While the United States population is composed of 18.5% Hispanics, they only account for 1% of patients enrolled in clinical trials. This study helps identify potential motivational factors for Hispanic patients to participate in skin cancer clinical trials.