# Retraction: Astragaloside IV (AS-IV) alleviates the malignant biological behavior of hepatocellular carcinoma via Wnt/β-catenin signaling pathway

**Authors:** ZhongYu Jiang, Zhen Mao

PMC · DOI: 10.1039/d4ra90047b · 2024-05-02

## TL;DR

This paper is a retraction of a previous study that claimed Astragaloside IV reduces liver cancer aggression through a specific signaling pathway.

## Contribution

The retraction highlights the correction or removal of previously published findings on Astragaloside IV's effect on hepatocellular carcinoma.

## Key findings

- The original study's claims about Astragaloside IV's impact on liver cancer were retracted.
- The retraction suggests potential issues with the validity of the original research findings.

## Abstract

Retraction of ‘Astragaloside IV (AS-IV) alleviates the malignant biological behavior of hepatocellular carcinoma via Wnt/β-catenin signaling pathway’ by ZhongYu Jiang et al., RSC Adv., 2019, 9, 35473–35482, https://doi.org/10.1039/C9RA05933D.

## Linked entities

- **Chemicals:** Astragaloside IV (PubChem CID 158694), AS-IV (PubChem CID 168314659)
- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Genes:** CTNNB1 (catenin beta 1) [NCBI Gene 1499] {aka CTNNB, EVR7, MRD19, NEDSDV, armadillo}
- **Diseases:** hepatocellular carcinoma (MESH:D006528)
- **Chemicals:** AS-IV (MESH:C052064)

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Source: https://tomesphere.com/paper/PMC11064781