# Editorial on common mental health disorders and cognitive decline in a longitudinal Down syndrome cohort

**Authors:** Samuel J. Tromans, Pushpal Desarkar

PMC · DOI: 10.1192/bjo.2024.16 · BJPsych Open · 2024-04-11

## TL;DR

This editorial discusses how mental health disorders in people with Down syndrome may affect the development of Alzheimer's disease symptoms over time.

## Contribution

The study highlights the potential link between common mental health disorders and cognitive decline in individuals with Down syndrome.

## Key findings

- The study investigates the impact of common mental disorders on Alzheimer's disease features in Down syndrome patients.
- Findings suggest a possible association between mental health and cognitive decline in this population.

## Abstract

This editorial discusses a study by Idris and colleagues, where the authors investigated the impact of common mental disorders (CMDs) among patients with Down syndrome, with respect to development of clinical features of Alzheimer's disease.

## Linked entities

- **Diseases:** Down syndrome (MONDO:0008608), Alzheimer's disease (MONDO:0004975)

## Full-text entities

- **Diseases:** Alzheimer's disease (MESH:D000544), CMDs (MESH:D001523), cognitive decline (MESH:D003072), Down syndrome (MESH:D004314), mental health disorders (OMIM:603663)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11060088/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11060088/full.md

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Source: https://tomesphere.com/paper/PMC11060088