# MR imaging findings of massive perivillous fibrin deposition of the placenta: A case report

**Authors:** Shinya Fujii, Naoko Mukuda, Hiroto Yunaga, Takuro Gonda, Takeru Fukunaga, Yuji Kamata, Ryoya Ochiai, Kanae Ozaki

PMC · DOI: 10.1016/j.radcr.2024.03.090 · Radiology Case Reports · 2024-04-24

## TL;DR

This paper presents MRI findings of a rare placental condition called massive perivillous fibrin deposition, which appears as hypointensity on T2-weighted images.

## Contribution

The study provides novel MRI characteristics of massive perivillous fibrin deposition in the placenta.

## Key findings

- MPFD appears as linear and geographical hypointensity on T2-weighted MRI.
- The hypointensity is likely due to extensive fibrin deposition in the intervillous space.
- The MRI findings may help identify MPFD in patients with a history of miscarriage.

## Abstract

Massive perivillous fibrin deposition (MPFD) of the placenta is characterized by the obliteration of the villous trophoblast with extensive deposition of fibrinoid material in the intervillous space. Here, we describe the MRI findings of a case of MPFD. The placenta demonstrates linear and geographical hypointensity on T2-weighted imaging, which is suggested to mainly reflect fibrin deposition. This finding should be noted, particularly in patients with miscarriage in their past history.

## Full-text entities

- **Diseases:** MPFD (MESH:D014202), miscarriage (MESH:D000022)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11059301/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11059301/full.md

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Source: https://tomesphere.com/paper/PMC11059301