# Management of COVID-19-Associated Acute Respiratory Distress Syndrome (ARDS) During Pregnancy Following In Vitro Fertilization (IVF)

**Authors:** Nika Vashakidze, Ana Mateshvili, Elene Pachkoria, Levan Ratiani

PMC · DOI: 10.7759/cureus.57223 · 2024-03-29

## TL;DR

This case report details the management of severe COVID-19 in a pregnant woman who conceived via IVF, highlighting the importance of a multidisciplinary approach to ensure positive outcomes for both mother and child.

## Contribution

The paper presents a unique case of IVF-conceived pregnancy complicated by severe COVID-19, emphasizing multidisciplinary management and no intrauterine transmission.

## Key findings

- The neonate tested negative for COVID-19, indicating no intrauterine transmission.
- Prompt interventions like mechanical ventilation and targeted antibiotics stabilized the patient's condition.
- Multidisciplinary collaboration and monitoring were critical for managing the complex case.

## Abstract

Coronavirus disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is recognized for its heterogeneous clinical presentation, complex pathophysiology, and broad spectrum of manifestations. Obstetric patients have been a subject of considerable interest due to their potential vulnerability to more severe infection and adverse pregnancy outcomes, exemplified by this report of a 43-year-old pregnant female with severe COVID-19 infection and respiratory complications. This case report aims to contribute to the existing scientific knowledge by presenting a detailed clinical profile of a patient with COVID-19 who achieved pregnancy through in vitro fertilization (IVF) and discussing the management and outcomes of the infection. The neonate's negative COVID-19 tests suggest no intrauterine transmission; prompt medical interventions, including mechanical ventilation and targeted antibiotic therapy, were implemented to stabilize her condition. Close collaboration among the multidisciplinary team and careful monitoring of vital functions and laboratory parameters were crucial in managing the patient's complex condition. Thus, this case highlights the importance of a comprehensive and multidisciplinary approach in managing severe COVID-19 cases in pregnancy, emphasizing the need for prompt recognition of complications and timely intervention.

## Linked entities

- **Diseases:** Coronavirus disease 2019 (MONDO:0100096), acute respiratory distress syndrome (MONDO:0006502), severe acute respiratory syndrome coronavirus 2 (MONDO:0100096)

## Full-text entities

- **Diseases:** ARDS (MESH:D012128), respiratory complications (MESH:D012140), COVID-19 (MESH:D000086382), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11056601/full.md

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Source: https://tomesphere.com/paper/PMC11056601