# A case of testicular cancer in a long‐term hydranencephaly survivor with undescended testes

**Authors:** Wataru Hirata, Toshiaki Shinojima, Kotaro Yokota, Rei Kin, Taketo Yamada, Hirotaka Asakura

PMC · DOI: 10.1002/iju5.12720 · 2024-04-01

## TL;DR

This paper reports the first case of testicular cancer in a long-term hydranencephaly survivor with undescended testes.

## Contribution

The paper presents the first documented case of testicular cancer in a hydranencephaly patient with undescended testes.

## Key findings

- A 32-year-old hydranencephaly survivor was diagnosed with testicular cancer in undescended testes.
- Surgical resection revealed a mixed-type germ cell tumor.
- Clinical ethics consultation is suggested to aid treatment decisions for such patients.

## Abstract

The development of malignant tumors in patients with hydranencephaly is extremely rare. We describe the first case of testicular cancer that developed in the undescended testes of a long‐term survivor of hydranencephaly.

A 32‐year‐old man with severe cerebral palsy due to hydranencephaly was referred to our department for the evaluation of a subcutaneous lump in the lower right abdomen. He was a long‐term survivor of hydranencephaly. After confirming the diagnosis of right testicular cancer originating in his undescended testes, surgical resection was performed. Pathological examination revealed a mixed‐type germ cell tumor.

The decision‐making process for treating malignant tumors, like testicular cancer, in adults with severe cerebral palsy can be challenging. Clinical ethics consultation could be helpful in avoiding treatment delays.

## Linked entities

- **Diseases:** testicular cancer (MONDO:0003510), hydranencephaly (MONDO:0016344), cerebral palsy (MONDO:0006497)

## Full-text entities

- **Diseases:** undescended testes (MESH:D003456), hydranencephaly (MESH:D006832), lump (MESH:C536531), right testicular cancer (MESH:D013736), cerebral palsy (MESH:D002547), malignant tumors (MESH:D009369), germ cell tumor (MESH:D009373)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11056246/full.md

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Source: https://tomesphere.com/paper/PMC11056246