# Rare Case of Tubercular Serpiginous-Like Choroiditis

**Authors:** Renu Magdum, Tushar Agrawal, Deepaswi Bhavsar, Nilesh Giri, Ozukhil Radhakrishnan

PMC · DOI: 10.7759/cureus.57093 · 2024-03-27

## TL;DR

This paper reports a rare case of eye inflammation caused by tuberculosis in an Indian man, successfully treated with steroids and anti-tuberculosis therapy.

## Contribution

The novelty lies in documenting a rare case of tubercular serpiginous-like choroiditis in an Indian patient and its successful treatment.

## Key findings

- The patient showed bilateral grey-yellowish subretinal infiltrates consistent with tubercular choroiditis.
- Treatment with steroids and anti-TB drugs led to complete healing of the lesions.
- The case highlights the importance of considering TB in diagnosing choroiditis in endemic regions.

## Abstract

Serpiginous choroiditis is a rare cause of posterior uveitis, included in the spectrum of white dot syndromes. It occurs as a result of an autoimmune process but could be associated with infections such as tuberculosis (TB) (serpiginous-like choroiditis). Tubercular serpiginous-like choroiditis is more commonly reported in Southeast Asian countries than in Western countries. We report a case of an Indian male in his late 30s with bilateral grey-yellowish subretinal infiltrates at the level of choroid with active scalloped edges having a positive TB-QuantiFERON Gold test (Cellestis Limited, Carnegie, Australia), who responded well to the treatment of intravenous methylprednisolone and systemic steroids (given initially to control the acute inflammation) while on anti-tubercular (anti-TB) therapy. The lesions finally completely healed on the anti-TB therapy.

## Linked entities

- **Chemicals:** methylprednisolone (PubChem CID 6741)
- **Diseases:** tuberculosis (MONDO:0018076), serpiginous choroiditis (MONDO:0018152), posterior uveitis (MONDO:0001280)

## Full-text entities

- **Diseases:** Tubercular Serpiginous-Like (MESH:D014390), Choroiditis (MESH:D002833), TB (MESH:D014376), Serpiginous choroiditis (MESH:D000080363), posterior uveitis (MESH:D015866), inflammation (MESH:D007249), subretinal infiltrates (MESH:D017254), infections (MESH:D007239)
- **Chemicals:** QuantiFERON Gold (-), steroids (MESH:D013256), methylprednisolone (MESH:D008775)

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11055604/full.md

---
Source: https://tomesphere.com/paper/PMC11055604