# Multifractal Analysis of Choroidal SDOCT Images in the Detection of Retinitis Pigmentosa

**Authors:** Francesca Minicucci, Fotios D. Oikonomou, Angela A. De Sanctis

PMC · DOI: 10.3390/tomography10040037 · Tomography · 2024-03-29

## TL;DR

This paper explores using multifractal analysis on choroidal images to detect retinitis pigmentosa early.

## Contribution

The novelty is applying multifractal analysis to choroidal SDOCT images for early RP diagnosis.

## Key findings

- Multifractal dimensions increase in RP patients compared to controls.
- Choroidal branching patterns show inhomogeneity measurable via Renyi dimensions.

## Abstract

The aim of this paper is to investigate whether a multifractal analysis can be applied to study choroidal blood vessels and help ophthalmologists in the early diagnosis of retinitis pigmentosa (RP). In a case study, we used spectral domain optical coherence tomography (SDOCT), which is a noninvasive and highly sensitive imaging technique of the retina and choroid. The image of a choroidal branching pattern can be regarded as a multifractal. Therefore, we calculated the generalized Renyi point-centered dimensions, which are considered a measure of the inhomogeneity of data, to prove that it increases in patients with RP as compared to those in the control group.

## Linked entities

- **Diseases:** retinitis pigmentosa (MONDO:0008377)

## Full-text entities

- **Diseases:** RP (MESH:D012174)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11053729/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC11053729/full.md

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Source: https://tomesphere.com/paper/PMC11053729