# Serum brain natriuretic peptide levels may be a useful marker for early diagnosis of cardiomyopathy secondary to neuroblastoma: A case report

**Authors:** Natsumi Fujiyama, Osamu Matsuo, Takahiro Yamashita, Kensaku Kohrogi, Fumiya Miyamura, Tadashi Anan, Kimitoshi Nakamura

PMC · DOI: 10.1002/ccr3.8738 · Clinical Case Reports · 2024-04-26

## TL;DR

High brain natriuretic peptide levels in blood may help detect early heart damage in infants with neuroblastoma.

## Contribution

This case report suggests BNP levels can aid in early diagnosis of cardiomyopathy in neuroblastoma patients.

## Key findings

- Elevated BNP levels indicated cardiomyopathy before heart failure symptoms worsened.
- A 5-month-old neuroblastoma patient developed dilated cardiomyopathy.

## Abstract

Cardiomyopathy is a rare but serious complication associated with neuroblastoma. The brain natriuretic peptide level led to a diagnosis of secondary dilated cardiomyopathy before the worsening of heart failure symptoms.

A 5‐month‐old boy with neuroblastoma showed dilated cardiomyopathy.

## Linked entities

- **Diseases:** cardiomyopathy (MONDO:0004994), neuroblastoma (MONDO:0005072)

## Full-text entities

- **Diseases:** dilated cardiomyopathy (MESH:D002311), heart failure (MESH:D006333), neuroblastoma (MESH:D009447), Cardiomyopathy (MESH:D009202)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11052679/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11052679/full.md

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Source: https://tomesphere.com/paper/PMC11052679