# Can Early Post-Operative Scoring of Non-Traumatic Amputees Decrease Rates of Revision Surgery?

**Authors:** Vesta Brauckmann, Ole Moritz Block, Luis A. Pardo, Wolfgang Lehmann, Frank Braatz, Gunther Felmerer, Sebastian Mönnighoff, Jennifer Ernst

PMC · DOI: 10.3390/medicina60040565 · Medicina · 2024-03-30

## TL;DR

This study creates a scoring system to identify non-traumatic amputees at risk for revision surgery, aiming to improve early decision-making and reduce revision rates.

## Contribution

The study introduces a novel scoring system for predicting revision surgery in non-traumatic amputees based on clinical and demographic risk factors.

## Key findings

- 27% of non-traumatic amputations required revision surgery.
- Key risk factors include peripheral vascular disease, diabetes, and delayed wound healing.
- A combined score was developed to identify patients at risk for revision surgery.

## Abstract

Background and Objectives: Medical registries evolved from a basic epidemiological data set to further applications allowing deriving decision making. Revision rates after non-traumatic amputation are high and dramatically impact the following rehabilitation of the amputee. Risk scores for revision surgery after non-traumatic lower limb amputation are still missing. The main objective was to create an amputation registry allowing us to determine risk factors for revision surgery after non-traumatic lower-limb amputation and to develop a score for an early detection and decision-making tool for the therapeutic course of patients at risk for non-traumatic lower limb amputation and/or revision surgery. Materials and Methods: Retrospective data analysis was of patients with major amputations lower limbs in a four-year interval at a University Hospital of maximum care. Medical records of 164 patients analysed demographics, comorbidities, and amputation-related factors. Descriptive statistics analysed demographics, prevalence of amputation level and comorbidities of non-traumatic lower limb amputees with and without revision surgery. Correlation analysis identified parameters determining revision surgery. Results: In 4 years, 199 major amputations were performed; 88% were amputated for non-traumatic reasons. A total of 27% of the non-traumatic cohort needed revision surgery. Peripheral vascular disease (PVD) (72%), atherosclerosis (69%), diabetes (42%), arterial hypertension (38%), overweight (BMI > 25), initial gangrene (47%), sepsis (19%), age > 68.2 years and nicotine abuse (17%) were set as relevant within this study and given a non-traumatic amputation score. Correlation analysis revealed delayed wound healing (confidence interval: 64.1% (47.18%; 78.8%)), a hospital length of stay before amputation of longer than 32 days (confidence interval: 32.3 (23.2; 41.3)), and a BKA amputation level (confidence interval: 74.4% (58%; 87%)) as risk factors for revision surgery after non-traumatic amputation. A combined score including all parameters was drafted to identify non-traumatic amputees at risk for revision surgery. Conclusions: Our results describe novel scoring systems for risk assessment for non-traumatic amputations and for revision surgery at non-traumatic amputations. It may be used after further prospective evaluation as an early-warning system for amputated limbs at risk of revision.

## Linked entities

- **Diseases:** Peripheral vascular disease (MONDO:0005294), atherosclerosis (MONDO:0005311), diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** atherosclerosis (MESH:D050197), nicotine abuse (MESH:D014029), overweight (MESH:D050177), sepsis (MESH:D018805), gangrene (MESH:D005734), diabetes (MESH:D003920), hypertension (MESH:D006973), amputation (MESH:C565682), PVD (MESH:D016491)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11052005/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11052005/full.md

## References

37 references — full list in the complete paper: https://tomesphere.com/paper/PMC11052005/full.md

---
Source: https://tomesphere.com/paper/PMC11052005