# The Effect of Intermittent Pneumatic Compression on Hemodynamics and Regional Cerebral Oxygen Saturation in Laparoscopic Bariatric Surgery with Mild Hypercapnia in the Steep Reverse Trendelenburg Position

**Authors:** Youn Yi Jo, Seong Min Kim, Chun Gon Park, Ji Woong Kim, Hyun Jeong Kwak

PMC · DOI: 10.3390/jpm14040405 · Journal of Personalized Medicine · 2024-04-11

## TL;DR

This study found that using intermittent pneumatic compression during bariatric surgery does not significantly improve blood pressure, heart rate, or brain oxygen levels in obese patients.

## Contribution

The study evaluates the effectiveness of IPC in improving hemodynamics and cerebral oxygenation in obese patients during bariatric surgery.

## Key findings

- IPC did not significantly reduce intraoperative hypotension compared to the control group.
- Changes in mean arterial pressure and heart rate over time were similar between the IPC and control groups.
- Cerebral desaturation events and oxygen saturation levels were not significantly different between groups.

## Abstract

Obesity negatively affects hemodynamics and cerebral physiology. We investigated the effect of the utilization of an intermittent pneumatic compression (IPC) device on hemodynamics and cerebral physiology in patients undergoing laparoscopic bariatric surgery under general anesthesia with lung-protective ventilation. Sixty-four patients (body mass index > 30 kg/m2) were randomly assigned to groups that received an IPC device (IPC group, n = 32) and did not (control group, n = 32). The mean arterial pressure (MAP), heart rate (HR), need for vasopressors, cerebral oxygen saturation (rSO2), and cerebral desaturation events were recorded. The incidence of intraoperative hypotension was not significantly different between groups (p = 0.153). Changes in MAP and HR over time were similar between groups (p = 0.196 and p = 0.705, respectively). The incidence of intraoperative cerebral desaturation was not significantly different between groups (p = 0.488). Changes in rSO2 over time were similar between the two groups (p = 0.190) during pneumoperitoneum. Applying IPC to patients with obesity in the steep reverse Trendelenburg position may not improve hemodynamic parameters, vasopressor requirements, or rSO2 values during pneumoperitoneum under lung-protective ventilation. During laparoscopic bariatric surgery, IPC alone has limitations in improving hemodynamics and cerebral physiology.

## Linked entities

- **Diseases:** obesity (MONDO:0011122)

## Full-text entities

- **Diseases:** cerebral desaturation (MESH:D002547), Hypercapnia (MESH:D006935), hypotension (MESH:D007022), Obesity (MESH:D009765)
- **Chemicals:** Oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11050837/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11050837/full.md

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Source: https://tomesphere.com/paper/PMC11050837