# Peripapillary Choroidal Neovascular Membrane: A Case Report

**Authors:** Rana S Alojair, Muhammed Amer, Abdulmajeed Alkhathami, Ibrahim N Asiri

PMC · DOI: 10.7759/cureus.57050 · Cureus · 2024-03-27

## TL;DR

A 60-year-old Saudi woman with a rare eye condition called peripapillary choroidal neovascular membrane showed improvement after treatment with aflibercept injections.

## Contribution

This paper reports a rare case of PCNM in Saudi Arabia and highlights the effectiveness of anti-VEGF treatment for this condition.

## Key findings

- The patient showed symptom improvement after aflibercept injections.
- Anti-VEGF treatment can preserve vision and improve anatomy in PCNM cases.
- Early diagnosis and treatment are crucial for managing PCNM.

## Abstract

Peripapillary choroidal neovascular membrane (PCNM) is an abnormal growth of blood vessels beneath the retina near the optic disc. We report a case of a 60-year-old Saudi female with a history of hypertension, hypothyroidism, and epilepsy who presented to the emergency room (ER), reporting a sudden decrease in vision over the past month. Ophthalmic examination revealed reduced visual acuity. The patient received aflibercept via intravitreal injection every four weeks. On follow-up, she reported improvement in symptoms. It has been shown that intravitreal anti-vascular endothelial growth factor (VEGF) not only preserves visual acuity but also produces anatomic improvement when used alone or in conjunction with other therapeutic modalities like photodynamic therapy, laser photocoagulation, and subretinal surgery, as PCNM is aberrant blood vessel growth under the retina. Only a few cases have been recorded in Saudi Arabia; we report this case to emphasize the importance of diagnosis and timely treatment with anti-VEGF.

## Linked entities

- **Diseases:** hypothyroidism (MONDO:0005420), epilepsy (MONDO:0005027)

## Full-text entities

- **Genes:** VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}
- **Diseases:** hypertension (MESH:D006973), hypothyroidism (MESH:D007037), epilepsy (MESH:D004827), PCNM (MESH:D020256), decrease in vision (MESH:D014786)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11050728/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11050728/full.md

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Source: https://tomesphere.com/paper/PMC11050728