# Clinical Approach to Patients with COVID-19 and Unrecognized Obstructive Sleep Apnea

## TL;DR

This study shows that undiagnosed sleep apnea may worsen COVID-19 outcomes, and treating it with CPAP can improve breathing and recovery.

## Contribution

The study highlights the novel link between undiagnosed obstructive sleep apnea and severe COVID-19, suggesting CPAP treatment as a potential intervention.

## Key findings

- All seven patients had severe obstructive sleep apnea confirmed by cardiorespiratory polygraphy.
- CPAP treatment improved overnight oxygenation and symptoms in patients with undiagnosed sleep apnea.
- Undiagnosed obstructive sleep apnea may worsen respiratory failure in COVID-19 patients.

## Abstract

Purpose: We conducted a retrospective case series of seven male COVID-19 patients with respiratory failure and suspected OSA based on clinical features to evaluate the effects of undiagnosed obstructive sleep apnea (OSA) on COVID-19 outcomes and the response to a continuous positive airway pressure (CPAP) treatment. Cardiorespiratory polygraphy (CRP) and a continuous positive airway pressure treatment were used for diagnosis and management. They confirmed severe obstructive sleep apnea in all patients (apnea/hypopnea index > 30) and improved overnight oxygenation and symptoms at the 1-month follow-up. Conclusions: Undiagnosed obstructive sleep apnea may negatively impact COVID-19 outcomes by exacerbating respiratory failure. Recognition and treatment with continuous positive airway pressure can optimize the management of such patients.