# Challenges of Secondary Glaucoma Management Following Congenital Cataract Surgery, Penetrating Keratoplasty and Vitreoretinal Surgery

**Authors:** Valeria Coviltir, Maria Cristina Marinescu, Miruna Gabriela Burcel, Maria-Emilia Cerghedean-Florea, Adrian Hașegan, Ciprian Tănăsescu, Mihaela Laura Vică, Horațiu Dura

PMC · DOI: 10.3390/diagnostics14080837 · 2024-04-18

## TL;DR

This paper discusses the challenges of managing secondary glaucoma in a patient with a complex eye history and highlights a successful treatment approach.

## Contribution

The paper presents a case study emphasizing the difficulties and successful management of secondary glaucoma after multiple eye surgeries.

## Key findings

- Secondary glaucoma in the patient's right eye remained refractory to maximal treatment and surgical interventions.
- Reimplantation of an Ahmed valve led to improved visual acuity and controlled intraocular pressure.
- Managing secondary glaucoma after aphakia and corneal graft is challenging and requires careful assessment.

## Abstract

Glaucoma is one of the world’s leading causes of irreversible vision loss. It is often asymptomatic until it reaches an advanced stage, which can have a significant impact on patients’ daily lives. This paper describes the case of a 50-year-old female patient who presented with acute onset of ocular pain, photophobia, and loss of visual acuity in her right eye (RE). The patient’s medical history includes congenital cataracts, surgical aphakia, nystagmus, strabismus, amblyopia, and secondary glaucoma. Ophthalmological examination showed BCVA RE-hand movement, left eye (LE)—0.08 with an intraocular pressure (IOP) of 30 mmHg in RE and 16 mmHg in LE. Biomicroscopic examination of RE showed corneal graft, epithelial and endothelial edema, endothelial precipitates, corneal neovascularization, aphakia, and Ahmed valve superotemporally. Despite maximal topical and systemic treatment, Ahmed valve, and trabeculectomy, secondary glaucoma in the right eye remained refractory. Reimplantation of an Ahmed valve was performed. This resulted in a favorable outcome with increased visual acuity and controlled intraocular pressure. The combination of aphakia, penetrating keratoplasty, and secondary glaucoma is a challenge for any surgeon. It is important that both the perioperative risks and the possible complications are carefully assessed in each patient, especially if associated pathology is present.

## Linked entities

- **Diseases:** glaucoma (MONDO:0005041), nystagmus (MONDO:0005712), strabismus (MONDO:0003432), amblyopia (MONDO:0001020)

## Full-text entities

- **Diseases:** Glaucoma (MESH:D005901), strabismus (MESH:D013285), corneal neovascularization (MESH:D016510), Cataract Surgery (MESH:D002386), RE (MESH:D005134), loss of visual acuity in (MESH:D014786), Ahmed valve (MESH:D006349), photophobia (MESH:D020795), aphakia (MESH:D001035), ocular pain (MESH:D058447), amblyopia (MESH:D000550), edema (MESH:D004487), nystagmus (MESH:D009759)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11049643/full.md

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Source: https://tomesphere.com/paper/PMC11049643