Myxofibrosarcoma of the Chest Wall Detected on 99mTc-MDP Whole-Body Bone Scan

TL;DR

A 73-year-old woman's chest wall myxofibrosarcoma was detected using a bone scan, showing unusual soft tissue uptake due to increased tumor vascularity.

Contribution

Demonstrates the utility of 99mTc-MDP bone scans in detecting myxofibrosarcoma through soft tissue uptake patterns.

Findings

99mTc-MDP bone scan showed marked uptake in the right lateral chest region due to tumor vascularity.

The imaging phenotype suggests bone scans can detect myxofibrosarcoma beyond typical bony metastasis.

The case highlights the potential of nuclear imaging in soft tissue sarcoma diagnosis.

Abstract

Myxofibrosarcoma is a type of soft tissue sarcoma, predominantly characterized by a high propensity for local recurrence, albeit demonstrating a relatively diminished risk for distant metastasis. Its prevalence is notably higher in elderly patients. Here, we present a case of a 73-year-old woman diagnosed with Myxofibrosarcoma. She was subjected to a whole-body bone scan using 99mTc-methylene diphosphonate (MDP) to survey potential bony metastasis. It revealed marked MDP accumulation with peripheral soft tissue uptake in the right lateral chest region of this patient. This imaging phenotype could potentially be attributed to the augmented vascularity within the tumor, a finding that was prominently displayed in this particular case.

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