# Bilateral Naevus of Ito and Ota With Palatal Involvement

## TL;DR

A 32-year-old man presented with rare bilateral skin conditions involving both his face and palate.

## Contribution

This is the first reported case of bilateral naevus of Ito and Ota with palatal involvement.

## Key findings

- Bilateral naevus of Ito and Ota was observed in a single patient.
- The patient had palatal involvement, a rare manifestation of naevus of Ota.
- No prior case with this combination of bilateral and oral involvement was found in English literature.

## Abstract

Naevus of Ito and naevus of Ota are benign dermal melanocytoses with similar pathogenic mechanisms of failure in the melanocyte migration to typical locations within the basal layer from neural crest cells and differ in distribution. Bilateral and oral mucosal involvement of naevus of Ota can occur but is infrequent. Naevus of Ito is seldom associated with naevus of Ota and extracutaneous manifestations. A review of the English literature showed 14 cases of naevus of Ota with palatal involvement. None showed bilateral involvement of both naevi with oral involvement. Here we report the case of bilateral naevus of Ito and bilateral naevus of Ota with palatal involvement. A 32-year-old male came to us with naevus of Ito on both sides of his back and naevus of Ota on both sides of his face involving the sclera of both eyes with a bluish lesion along the midline of the hard palate.