# Navigating challenges in diagnosing acquired hemophilia A: A case report from Syria

**Authors:** Oubai Nayouf, Miriam Laflouf, Ibrahim Hamdan, Ibrahim Alghazawi, Omar Aldairi, Ameen Sulaiman

PMC · DOI: 10.1002/ccr3.8811 · 2024-04-24

## TL;DR

This case report highlights the importance of early diagnosis and treatment for a rare bleeding disorder called acquired hemophilia A.

## Contribution

The paper emphasizes the diagnostic and management challenges of acquired hemophilia A in a specific geographic context.

## Key findings

- Rapid diagnosis using aPTT and FVIII tests is essential for acquired hemophilia A.
- Immediate treatment with bypassing agents and steroids improves patient outcomes.

## Abstract

Acquired hemophilia A is a rare bleeding disorder. Rapid diagnosis with prolonged aPTT and low FVIII, and immediate use of bypassing agents and steroids are crucial for better outcomes, highlighting the importance of early recognition and management.

Early diagnosis and intervention are crucial for better outcomes in acquired hemophilia A.

## Linked entities

- **Proteins:** F8 (coagulation factor VIII)
- **Diseases:** acquired hemophilia A (MONDO:0035735)

## Full-text entities

- **Genes:** F8 (coagulation factor VIII) [NCBI Gene 2157] {aka AHF, DXS1253E, F8B, F8C, FVIII, HEMA}
- **Diseases:** Acquired hemophilia A (MESH:C536392), bleeding disorder (MESH:D006470)
- **Chemicals:** steroids (MESH:D013256)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11043089/full.md

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Source: https://tomesphere.com/paper/PMC11043089